🏆Experts in sport nutrition since 1993🏆

Ubiquinol Q10

£39.95
  • High-quality Ubiquinol Kaneka
  • Improved sports performances
  • Improved cardiovascular health
  • Ideal against statin-related pain
  • Essential supplement for over 40s
100% quality Coenzyme Q10 produced by Kaneka Find out more
  • Anti-inflammatory
  • +
  • Antioxidant
  • Heart
  • Longevity
  • +
  • Recovery
  • Capsules
  • Powder
Amount
  • 30 Capsules
  • 60 Capsules
  • 120 Capsules
  • 400 Capsules
  • 60 g
  • 150 g
  • 350 g
Optimal consumption date: 04/2023
£39.95
Quantity
- 1 +
  • Product offered from £50 purchase
  • Free delivery

Description

What is ubiquinol?

Ubiquinol is the most antioxidant form of coenzyme Q10 for performance, health, and longevity. Q10 is a vitamin-like molecule (vitamin K) that is present in cell membranes and acts as an antioxidant and anti-inflammatory.  

More specifically, Q10 helps mitochondria produce ATP. By stimulating energy production, Q10 helps the most important of our muscles, the heart, to function properly. It also reduces the formation of fibrosis, which helps maintain good cardiovascular health over the decades.

What are the benefits of ubiquinol?

Boosted performance

The beneficial effects of Q10 on performance are especially noted with endurance sports. Q10 protects the muscles of elite athletes from muscular and hepatic catabolism. That's why the Q10 speeds up recovery between workouts. 

Cardiovascular Health

By stimulating energy production, Q10 helps the most important of our muscles, the heart, to function properly. It also reduces the formation of fibrosis, which helps maintain good cardiovascular health over the decades.

Health protection for athletes

Thanks to its antioxidant action, Q10 can protect the joints by reducing the rate of cartilage deterioration, thus reducing the level of pain you suffer.

For further details on the benefits of ubiquinol, visit the Find out more section.

Nutritional composition of ubiquinol

Nutritional values per 100 g

Ubiquinol powder:

  • Protein : 0,9g
  • Carbohydrates : 96,1g
  • Fat : 0,3g 
  • Calories : 337 kcal

Ubiquinol capsules:

  • Protein 0.9 g
  • Fat 0.3 g
  • Carbohydrates 96.1 g
  • Calories 330 kcal
  • BCAA 0 g

1/2 a scoop contains 500 mg of Kaneka P30 ubiquinol (guar gum micro-capsules) or 150 mg of pure ubiquinol.
1 capsule contains 500 mg of Kaneka P30 ubiquinol (guar gum micro-capsules) or 150 mg of pure ubiquinol.

Ingredients

Ubiquinol powder: 

  • Kaneka P30 ubiquinol (70% guar gum micro-capsules)
  • Prebiotics: Frutafit® HD inulin.

Ubiquinol capsules:

  • Kaneka P30 ubiquinol
  • Prebiotics: Frutafit® HD inulin (70% guar gum micro-capsules)
  • Beef gelatin capsule.

Composition

Nutritional composition

100 g1 capsule
1 doser1/2 doser
Proteins0,9 g6,3 mg9 mg4,5 mg
Carbohydrates
96,1 g672,7 mg961 mg480,5 mg
- Of which fibers
74,6 g527,1 mg746 mg373 mg
Fats0,3 g2,1 mg3 mg1,5 mg
Calories337 kcal2,3 kcal3,2 kcal1,6 kcal
Energy
1409 kJ
8,3 kJ14 kJ7 kJ
  • 1 g (gram) = 1000 mg (milligram)
  • 1 capsule contains 500 mg of Kaneka Ubiquinol P30 or 150 mg of pure Ubiquinol.
  • 1/2 scoop contains 500 mg of Kaneka Ubiquinol P30, i.e. 150 mg of pure Ubiquinol. 
  • 1 scoop contains 1000 mg of Kaneka Ubiquinol P30, i.e. 300 mg of pure Ubiquinol. 

Usage tips

Who is Nutrimuscle ubiquinol for?

Nutrimuscle ubiquinol is for:

  • Athletes, to increase sports performance
  • Inactive people, to improve cardiovascular health

Dosage

Take ½ a scoop or 1 capsule per day.

Side effects
Cytotoxic tests show zero toxicity for ubiquinol, even at very high doses (120 times higher than that recommended for supplementation).

When should I take Nutrimuscle ubiquinol?

We recommend taking ubiquinol with a meal (morning, noon, or evening).

How do I take Nutrimuscle Ubiquinol?

The big advantage of Q10 is that it can be taken orally, which is standard for supplementation. It is recommended that you start with 100 mg a day. Due to its fat-soluble nature, we recommend consuming Q10 with a meal as high in fat as possible. After a week or two, if you aren't seeing results, switch to 200 mg daily, again for a week or two.

It is important to remember that if Q10 doesn't seem to be effective, it may simply be that you aren't absorbing it well enough. In this case, we suggest increasing your doses by taking it more often.

Should I use ubiquinol continuously or in cycles?

Ideally, in order to fully benefit from the anti-ageing, performance-enhancing, and health effects of Q10, it should be used continuously.

However, Q10 is an expensive molecule. Taking it in cycles is one way to reduce the cost of supplementation. The question is all the more important since medical research shows that some of the effects of a treatment plan last for a long time after supplementation has been stopped.

More than 400 senior citizens received either a placebo or 200 mg of Q10 + 200 μg of selenium daily for 4 years. Over the following 5 years, cardiac mortality was halved in the Q10 group compared to the placebo group (39).

A follow-up 10 years later still shows a decrease in cardiac mortality and overall mortality in the group that took Q10 (40). More surprisingly, 12 years after stopping supplementation, cardiovascular mortality was 39% in the placebo group versus 28% in the group that took Q10 (41). The action is more pronounced in women than in men, perhaps because they have naturally lower Q10 levels than men.

Interactions with other Nutrimuscle products

Synergies between supplements

For patients with mild cognitive impairment due to Parkinson's disease, a multi-year treatment of a combination of creatine + Q10 delayed cerebral degeneration compared to those taking a placebo. It is therefore a great combination to protect the brain from ageing.

Adverse reactions between supplements

No notable adverse reactions.

Scientific references

  • (39) Alehagen U. Cardiovascular mortality and N-terminal-proBNP reduced after combined selenium and coenzyme Q10 supplementation: a 5-year prospective randomized double-blind placebo-controlled trial among elderly Swedish citizens. Int J Cardiol. 2013 Sep 1;167(5):1860-6.
  • (40) Alehagen U. Reduced Cardiovascular Mortality 10 Years after Supplementation with Selenium and coenzyme Q10 for Four Years: Follow-Up Results of a Prospective Randomized Double-Blind Placebo-Controlled Trial in Elderly Citizens. PLoS One. 2015; 10(12): e0141641.
  • (41) Alehagen U. Still reduced cardiovascular mortality 12 years after supplementation with selenium and coenzyme Q10 for four years: A validation of previous 10-year follow-up results of a prospective randomized double-blind placebo-controlled trial in elderly. PLoS One. 2018; 13(4): e0193120.
  • (42) Deshmukh G. Safety Assessment of ubiquinol Acetate: Subchronic Toxicity and Genotoxicity Studies. J Toxicol. 2019 Apr 1.
  • (43) Fu X. Acute, subacute toxicity and genotoxic effect of Bio-Quinone® Q10 in mice and rats. Regulatory Toxicology and Pharmacology. 2009;53(1):1–5.
  • (44) Hatakeyama S. Comparative oral toxicity of coenzyme Q10 and its (2Z)-isomer in rats: single and four-week repeated dose toxicity studies. Journal of Nutritional Science and Vitaminology. 2006;52(1):9–20.
  • (45) Li Z. The effect of creatine and coenzyme q10 combination therapy on mild cognitive impairment in Parkinson’s disease. Eur Neurol. 2015;73(3-4):205-11.

Find out more

Q10 and ubiquinol: origin and derivatives

Be careful not to confuse Kaneka Ubiquinol and Kaneka Q10

Kaneka produces both ubiquinol and Q10. Q10 is the first form that was synthesized 30 years ago, so it is much older and less expensive. However, it is less effective than ubiquinol. Some retailers play on this ambiguity between ubiquinol and Kaneka Q10 and pass off their Q10 as ubiquinol to make their product look cheaper.

Is ubiquinol produced in France?

Many brands boast of made-in-France ubiquinol. Again, they play on words as well as consumer ignorance. Ubiquinol Kaneka comes from Japan. The other Q10s usually come from China. The only thing that is French is the packaging.

Ubiquinol versus Ubiquinone

In the body, we find three forms of Q10: oxidized Q10 (ubiquinone), radical Q10 (semiquinone), and reduced Q10 (ubiquinol). Similarly, there are three main forms of Q10 supplements: Q10, ubiquinol, and ubiquinone. The last two are the most popular, as they are newer forms than the old Q10.

Since the words ubiquinol and ubiquinone are similar, it's easy to lose track of which is which. Remember the hard NONE sound at the end of ubiquinone. It's a good way to help you remember the difference. The negative connotation of 'none' will remind you that while this form is the least expensive, it is also less effective, as the following studies illustrate.

In subjects aged 29 to 50 years, taking 200 mg of ubiquinol for 4 weeks raises blood levels of Q10 twice as much as taking 200 mg of ubiquiNONE (37). Men with an average age of 55 were given 200 mg of either ubiquinol or ubiquiNONE with a meal for 2 weeks. Taking ubiquinol increased the level of ubiquinol in the blood by 250% compared to 168% when taking ubiquiNONE (38). Taking ubiquinol increases the level of ubiquinone in the blood by 272% compared to 136% after taking ubiquiNONE.

We highlight, however, that there are very wide variations in the level of absorption between individuals, but 60% of subjects responded much better to ubiquinol, compared to 40% who absorbed ubiquiNONE better. Above-average levels of absorption are noted in 70% of ubiquinol users compared to only 20% of ubiquiNONE users (38).

Benefits of ubiquinol in more detail

Q10 is a vitamin-like molecule (vitamin K) (2). Q10 is present in cell membranes to act as an antioxidant and anti-inflammatory element. More specifically, Q10 helps mitochondria produce ATP. By stimulating the production of energy, Q10 helps our most important muscle to function well: the heart (4-5-6). It also reduces the formation of fibrosis, which helps to maintain good cardiovascular health over the years (7).

For example, for senior citizens with heart problems, taking Q10 for 2 years reduces mortality almost by half (18% in the placebo group versus 10% with Q10) (8-9).

These cardiac benefits of Q10 are excellent for athletes. While moderate exercise is good for the heart, we really put this muscle to the test when our training sessions become intense and regular. This explains why athletes, as they age, develop specific cardiac pathologies, which are rarely found among the less active population.

Q10 and sports performance
Medical analyses show that physical activity immediately lowers body Q10 levels due to an acceleration of the destruction of this molecule (12). This explains why lower Q10 rates are found in athletes in training compared to sedentary individuals (13-14-15-16). This is paradoxical, because studies show that the richer the muscles are in Q10, the better they perform. Hence the idea of supplementation to not only inhibit Q10 depletion, but also to increase performance (17-18).

These paradoxes of ageing and athletes are two example showing that our bodies do not function at their optimal levels without outside help from a supplement. Senior citizens and athletes suffer from lower Q10 reserves, while they need more than the average. Obviously there will be an accumulation of shortfalls among athletes as they get older.

The medical use of statins to lower cholesterol produces several side effects. Many patients develop muscle pain and weakness (19-20). One of the reasons for these problems is the drop in Q10 levels induced by these drugs. It is therefore a good model to better understand what happens when you're lacking Q10 and exactly what compensating for this deficit via supplementation does inside your body. Taking Q10 reduces muscle pain in 75% of statin users and general pain levels by 30-40% (21). Taking Q10 often facilitates improvement in muscular performance (22). 

But what about healthy athletes?

The beneficial effect of Q10 on performance is especially noted in endurance sports because medical research focuses on aerobic performance and not on muscle development (23-24-25-26).

Q10 protects muscles from both muscular and hepatic catabolism for high level athletes due to an alleviation of inflammatory and oxidative issues (27-28-29-30). These protective effects explain, at least partially, the reason why Q10 accelerates recovery between training sessions, which is a practical application for all athletes, including in strength disciplines such as weight training (31).

Health protection for athletes

Alone or in synergy with carnitine, Q10 alleviates the immune suppression observed after very intense efforts (32-33-34). Q10 also reduces the hypertension that develops during periods of very intensive training (35). Presumably because of its antioxidant action, Q10 may protect the joints by reducing the rate of cartilage deterioration, thereby reducing pain (36).

Scientific references

  • (1) Mantle D. coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview. Antioxidants (Basel). 2019 Feb 16;8(2). pii: E44.
  • (2) Shraddha S. CoQ10 a super-vitamin: review on application and biosynthesis. 3 Biotech. 2018 May; 8(5): 249.
  • (3) Farsi F. Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials. Pharmacol Res. 2019
  • (4) Sharma A. coenzyme Q10 and Heart Failure: A State-of-the-Art Review. Circ Heart Fail. 2016 Apr;9(4):e002639.
  • (5) Zozina VI. coenzyme Q10 in Cardiovascular and Metabolic Diseases: Current State of the Problem. Curr Cardiol Rev. 2018;14(3):164-174.
  • (6) Jafari M. coenzyme Q10 in the treatment of heart failure: A systematic review of systematic reviews. Indian Heart J. 2018 Jul;70 Suppl 1:S111-S117.
  • (7) Hargreaves IP. coenzyme Q10 Supplementation in Fibrosis and Aging. Adv Exp Med Biol. 2019;1178:103-112.
  • (8)Mortensen SA. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial. JACC Heart Fail. 2014 Dec;2(6):641-9.
  • (9) Mortensen AL. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial. Cardiol J. 2019;26(2):147-156.
  • (10)Kalén A. Age-related changes in the lipid compositions of rat and human tissues. Lipids. 1989 Jul;24(7):579-84.
  • (11) Miles MV. Age-related changes in plasma coenzyme Q10 concentrations and redox state in apparently healthy children and adults. Clin Chim Acta. 2004 Sep;347(1-2):139-44.
  • (12) Orlando P. Effect of ubiquinol supplementation on biochemical and oxidative stress indexes after intense exercise in young athletes. Redox Rep. 2018 Dec;23(1):136-145.
  • (13) Littarru GP. coenzyme Q10: blood levels and metabolic demand. Int J Tissue React. 1990;12(3):145-8.
  • (14) Karlsson J. Plasma ubiquinone, alpha-tocopherol and cholesterol in man. Int J Vitam Nutr Res. 1992;62(2):160-4.
  • (15) Battino M. Metabolic and antioxidant markers in the plasma of sportsmen from a Mediterranean town performing non-agonistic activity. Mol Aspects Med. 1997;18 Suppl:S241-5.
  • (16) Kaikkonen J. Determinants of plasma coenzyme Q10 in humans. FEBS Lett. 1999 Jan 25;443(2):163-6.
  • (17) Karlsson J. Muscle ubiquinone in healthy physically active males. Mol Cell Biochem. 1996 ;156:169-172.
  • (18) Laaksonen R. Serum and muscle tissue ubiquinone levels in healthy subjects. J Lab Clin Med. 1995;125:517-521.
  • (19) Loenneke JP. Statin use may reduce lower extremily peak force via reduced engagement in muscle-strenghthening activities. Clin Physiol Funct. 2016;38(1):151-154.
  • (20) Dunphy L. Rhabdomyolysis-induced compartment syndrome secondary to atorvastatin and strenuous exercise. BMJ Case Rep. 2017
  • (21) Skarlovnik A. coenzyme Q10 supplementation decreases statin-related mild-to-moderate muscle symptoms: a randomized clinical study. Med Sci Monit. 2014 Nov 6;20:2183-8.
  • (22) Deichmann RE. Impact of coenzyme Q-10 on parameters of cardiorespiratory fitness and muscle performance in older athletes taking statins. Phys Sportsmed. 2012 Nov;40(4):88-95.
  • (23) Gül I. Oxidative stress and antioxidant defense in plasma after repeated bouts of supramaximal exercise: the effect of coenzyme Q10. J Sports Med Phys Fitness. 2011 Jun;51(2):305-12
  • (24) Malm C. Effect of ubiquinone-10 supplementation and high intensity training on physical performance in humans. Acta Physiol Scand. 1997;161:379–384
  • (25) Cooke M. Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals. J Int Soc Sports Nutr. 2008;4:5-8.
  • (26) Gökbel H. The effects of coenzyme Q10 supplementation on performance during repeated bouts of supramaximal exercise in sedentary men. J Strength Cond Res. 2010;24:97-102.
  • (27) Emami A. Effect of oral CoQ10 supplementation along with precooling strategy on cellular response to oxidative stress in elite swimmers. Food Funct. 2018 Aug 15;9(8):4384-4393.
  • (28) Emami A. The Impact of Pre-Cooling and CoQ10 Supplementation on Mediators of Inflammatory Cytokines in Elite Swimmers. Nutr Cancer. 2019 May 16:1-11.
  • (29) Díaz-Castro J. coenzyme Q(10) supplementation ameliorates inflammatory signaling and oxidative stress associated with strenuous exercise. Eur J Nutr. 2012 Oct;51(7):791-9.
  • (30) Kon M. Reducing exercise-induced muscular injury in kendo athletes with supplementation of coenzyme Q10. Br J Nutr. 2008 Oct;100(4):903-9.
  • (31) Sarmiento A. Short-term ubiquinol supplementation reduces oxidative stress associated with strenuous exercise in healthy adults: A randomized trial. Biofactors. 2016 Nov 12;42(6):612-622.
  • (32) Trushina EN. [Immunomodulating effects of using L-carnitine and coenzyme Q10 in the nutrition of junior athletes]. Vopr Pitan. 2019;88(2):40-49.
  • (33) Pala R. coenzyme Q10 Supplementation Modulates NFκB and Nrf2 Pathways in Exercise Training. J Sports Sci Med. 2016 Feb 23;15(1):196-203.
  • (34) Shimizu K. coenzyme Q10 supplementation downregulates the increase of monocytes expressing toll-like receptor 4 in response to 6-day intensive training in kendo athletes. Appl Physiol Nutr Metab. 2015 Jun;40(6):575-81.
  • (35) Kizaki K. Effect of reduced coenzyme Q10 (ubiquinol) supplementation on blood pressure and muscle damage during kendo training camp: a double-blind, randomized controlled study. J Sports Med Phys Fitness. 2015 Jul-Aug;55(7-8):797-804.
  • (36) Nachvak SM. Effects of coenzyme Q10 supplementation on matrix metalloproteinases and DAS-28 in patients with rheumatoid arthritis: a randomized, double-blind, placebo-controlled clinical trial. Clin Rheumatol. 2019 Aug 7.
  • (37) Langsjoen PH. Comparison study of plasma coenzyme Q10 levels in healthy subjects supplemented with ubiquinol versus ubiquinone. Clin Pharmacol Drug Dev. 2014 Jan;3(1):13-7.
  • (38) Zhang Y. ubiquinol is superior to ubiquinone to enhance coenzyme Q10 status in older men. Food Funct. 2018 Nov 14;9(11):5653-5659.

Reviews

Transparency
Suppliers and
studies available
Conceived in France
& made in Belgium
0% Additives
0% Excipients
100% quality raw materials
Free delivery
to the United Kingdom