🏆Expert in Sports Nutrition since 1993🏆

Vitamin K2-MK7

£14.95
  • High-quality European production
  • For bone strength and longevity
  • Synergy with multivitamins and collagen!
  • The best assimilated form of K2-MK7
The Best Form of Vitamin K2 for Strong Bones and Good Health Find out more
  • Bone structure
  • +
  • Immunity
  • Longevity
  • Capsules
Amount
  • 60 Capsules
  • 120 Capsules
  • 400 Capsules
  • 800 Capsules
  • 1600 Capsules
Optimal consumption date: 07/2022
£14.95
Quantity
- 1 +
  • Product offered from £50 purchase
  • Free delivery

Description

Why choose Nutrimuscle's vitamin K2?

Special features of Nutrimuscle vitamin K2
A significant characteristic of Nutrimuscle's vitamin K2 compared to others is that it is not a low-cost Chinese generic product, but a patented vitamin K2, which has therefore been much more carefully analysed and used in numerous scientific studies. Moreover, it's made in Europe.  

Why choose MK-7 vitamin K2?
There are several variants of vitamin K2 available. But there are numerous reasons to opt for vitamin K2 MK-7. Compared to other K vitamins, K2 MK-7 has a better bioavailability (it is much better absorbed than the others) and has a longer half-life (it stays longer in the body, so it has more time to work compared to other rather fleeting K2 vitamins, because they are quickly eliminated (32 - 33 - 34)).

What are the benefits of Nutrimuscle's vitamin K2?

What are the health benefits of vitamin K2?

Research today shows that the need for vitamin K2 increases as we get older, as it counteracts many of the factors of ageing such as inflammatory issues, joint pain, calcification of the vessels, diminished bone strength, and cerebral deterioration (4 - 5 - 6 - 7).

Vitamin K2: bone strength

Vitamin K2 acts as a distributor of calcium deposits. Thanks to vitamin K2, instead of settling in the arteries, calcium can reach the bones and strengthen them (25). On the contrary, a low vitamin K2 intake in senior citizens accelerates the onset of osteoporosis.

Vitamin K2 and longevity

A Spanish study conducted over 5 years with more than 7000 people also showed that the higher a person's vitamin K2 intake, the lower their risk of cancer and mortality (26). Beyond the effects on cardiovascular and bone diseases, a high vitamin K2 intake is associated with a lower risk of metabolic disease (27).

Nutritional composition of Nutrimuscle vitamin K2-MK7

Nutritional composition per 100 g:

  • Protein 0 g
  • Fat 0 g
  • Carbohydrates 0 g
  • Calories 0 kcal

Ingredients

Vitamin K2-MK7 capsules:

  • Frutafit® HD Inulin
  • Vitamin K2-MK7 (menaquinone 7)
  • Vegetarian HPMC capsule and water.

Nutrimuscle vegetarian capsules
100% vegetable cellulose 
Gelatin free
GMO free
No preservatives 
Allergen free
Gluten-free
Sugar free
Starch free

How much vitamin K2 is in the MK-7 version?

Although they have always been present and their importance to health has always existed, doctors are not yet able to set an official threshold for minimum intake of K1 and K2 as they do for other vitamins.

Studies, both short term and long term, do not detect any side effects to the intake of vitamin K2, even at high doses (35 - 36 - 37 - 38).

It seems prudent to us, for athletes not receiving drug treatment based on anticoagulants, to regularly use a vitamin K cocktail comprising both vitamin K1 and especially K2.

The need for vitamin K supplementation is even greater in endurance athletes prone to demineralization (swimmers, cyclists, marathon runners ...).

Composition

Nutritional composition of Nutrimuscle vitamin K2-MK7

1 capsuleAJR*
Vitamin K2-MK7100 mcg133%

1 capsule contains 100 mcg (or µg) of vitamin K2-MK7 -

Usage tips

Who is Nutrimuscle Vitamin K2-MK7 for?

Nutrimuscle Vitamin K2-MK7 is for:

  • Athletes, who need more K2 vitamins than sedentary people
  • Sedentary people, as a nutritional supplement for its effects on longevity and bone mass protection

Dosage

Take 1 Nutrimuscle vitamin K2-MK7 capsule per day.

When should I take Nutrimuscle Vitamin K2-MK7?

In the morning with breakfast is best.

How do I take Nutrimuscle Vitamin K2-MK7?

Since vitamins take effect in the long term, it is preferable to do the following:
follow prolonged treatment plans
that span the duration of your intense training.
Short treatments of just a few weeks are not really appropriate.

Interactions with other Nutrimuscle products

Synergies between supplements
As collagen is a major constituent of our bones, vitamin K2 acts in synergy with Peptan Collagen Peptide (type-1 as well as type-IIm, which has a more targeted effect on cartilage) to promote bone strength.

Similarly, vitamin D significantly enhances the effects of vitamin K2 on bone strength (39).
Vitamin K2 is to be taken with multivitamins, which contain vitamin K1. K2 therefore does not simply duplicate the effect of our multivitamins. On the contrary, it reinforces it.

Adverse reactions between supplements
Anti-cholesterol drugs and antibiotics reduce vitamin K2 absorption. These drugs therefore increase your need for vitamin K2.

Find out more

All about the unique properties of vitamin K2

K vitamins are fat-soluble (diluted in fat). It was long thought that the only function of vitamin K was to act, via the liver, as a blood anticoagulant. But the hepatic effect of vitamin K is only represents a fraction of its benefits to our health. 

Understanding the different K vitamins
Little is known about K group vitamins, as it is only fairly recently that scientific research uncovered their super-hepatic roles, which are essential for our health. There are two main types of vitamin K: vitamin K1 and vitamin K2.

Despite the greater importance of K2 compared to K1 when it comes to our health, there are very few foods that provide vitamin K2. It is found in animal products (meat, egg yolks, hard cheeses, etc.) and in fermented products. But though they are indeed present, they areis is in very small quantities (1). Another tiny amount is made in our intestines. 

The vitamin K deficiency level of the general population is difficult to assess, but it could affect about 30% (if we're being generous) or even 70% of people (as a worst-case scenario; 2). 

Adults over 40 and children have the greatest vitamin K deficiencies. Because of these increased requirements, they are the most responsive to vitamin K2 supplementation (3).

Similarly, vegans, as well as those with intestinal problems such as coeliac disease, have higher than average needs.

How do I combat calcification?

Vitamin K2 acts first and foremost as a vascular protector by promoting the deposition of calcium in the bones (where it is useful), while inhibiting it in the blood vessels (where it is harmful). A vitamin K deficiency produces the opposite effect by facilitating vascular deposits, to the detriment of bone deposits, which is doubly negative for our health, especially for athletes.

When calcium deposits clog our arteries, it is not down to bad luck or because we've consumed too much. Calcium deposits are highly regulated phenomena. The main regulator is a protein called matrix-gla-protein (MGP), which is produced within the cells of the vascular walls and inhibits calcification.

The deposit-inhibiting effect of this protein depends on your vitamin K (and more importantly vitamin K2) intake. The more vitamin K2 there is in your diet, the more powerful the MGP ant-deposit effect is. On the other hand, when vitamin K2 is lacking, MGP is not very active, and therefore not available enough to fight against vascular calcium deposits. 

Does vitamin K2 combat cardiovascular problems?
Taking vitamin K2 reduces calcification and therefore many cardiovascular diseases. It is largely due to this effect that vitamin K2 reduces mortality (8).
A study carried out in 168 countries including men and women aged 15-64 shows that a low vitamin K2 intake (less than 5µg per 2000 calories per day) doubles the risk of death from cardiovascular disease compared to people consuming 5 times more vitamin K2 (9).

On the contrary, a high intake of vitamin K2 leads to a reduced risk of peripheral artery disease (10 - 11 - 12 - 13).

Is there a correlation between kidney stones and artery calcification?
Statistical medical studies show that people with kidney stones have an above-average risk of artery calcification (14).
Vitamin K (vitamin K1 as well as vitamin K2) can help them fight both these stones and calcification (15 - 16).

Sport and vitamin K2, which synergies for which problem?

Is sport good for health, especially heart?

A popular belief says that sport is good for your health! If it is true that the repetition of moderate physical efforts promotes cardiovascular health, as soon as you push the machine, and that, whatever the sport, the effects on the heart will no longer be of a single order: it there will be some good, but also some bad (17).

Thus, much greater calcifications are found in good level marathoners than in sedentary people of the same age (18).

A 25-year follow-up of people practicing endurance sports shows that the most assiduous athletes are also those who have the arteries most clogged with calcium (19).

These results, which might seem paradoxical, have been confirmed by several other studies (20 - 21).

Strength training, arterial stiffness and calcification

Unlike moderate endurance work which tends to reduce arterial stiffness, weight training and more generally strength training tend to increase arterial stiffness over the long term. This is normal, because the heavier you train, the more sudden a rise in tension (22 - 23).

In order to prevent "surges" from causing bleeding, the arterial walls strengthen instead of remaining thin and fragile. In exchange for this solidification, they lose their flexibility. This long-term reaction is not necessarily pathological, as it is a normal physiological response. On the other hand, if calcification is added to this over-rigidity, the cocktail risks becoming explosive and can easily lead to heart problems (24).

In this context, bodybuilding or even intense endurance work, continuous vitamin K2 supplementation takes on its full meaning.

Role of lack of vitamin K2 in increasing the risk of diabetes?

Vitamin K2 supports insulin in its effects, especially at the muscle level, for the maintenance of normal blood sugar levels in the short and long term (28).

This explains why people with diabetes have lower vitamin K2 levels than others. Besides a poor diet, studies show that their intestinal capacity to synthesize vitamin K2 is abnormally low (29).

This double phenomenon explains why research shows that vitamin K2 has many benefits in diabetics (30 - 31).

About Nutrimuscle Vitamin K2-MK7

We have chosen vitamin K2-MK7 from producer Nattopharma for its patented excellent quality form MenaQ7 Natural.

Scientific References

  • (1) Simes DC. Vitamin K as a Diet Supplement with Impact in Human Health: Current Evidence in Age-Related Diseases. Nutrients 2020, 12(1), 138
  • (2) Riphagen IJ. Prevalence and Effects of Functional Vitamin K Insufficiency: The PREVEND Study. Nutrients. 2017 Dec 8;9(12):1334.
  • (3) Theuwissen  E. Vitamin K Status in Healthy Volunteers. Food Funct. 2014 Feb;5(2):229-34.
  • (4) Schwalfenberg GK. Vitamins K1 and K2: The Emerging Group of Vitamins Required for Human Health. J Nutr Metab. 2017;2017:6254836. 
  • (5) Shea MK. The association between vitamin K status and knee osteoarthritis features in older adults: The Health, Aging and Body Composition Study. Osteoarthr. Cartil. 2016, 23, 370–378
  • (6) Zhang S. Vitamin K status and cardiovascular events or mortality: A meta-analysis. Eur. J. Prev. Cardiol. 2019, 26, 549–553.
  • (7) Alisi L. The Relationships Between Vitamin K and Cognition: A Review of Current Evidence
  • Front. Neurol., 19 March 2019  
  • (8) Roumeliotis S. Association of the Inactive Circulating Matrix Gla Protein with Vitamin K Intake, Calcification, Mortality, and Cardiovascular Disease: A Review. Int J Mol Sci. 2019 Feb; 20(3): 628.
  • (9) Cundiff DK. Cardiovascular Disease Death Before Age 65 in 168 Countries Correlated Statistically With Biometrics, Socioeconomic Status, Tobacco, Gender, Exercise, Macronutrients, and Vitamin K. Cureus . 2016 Aug 24;8(8):e748.
  • (10)Vissers LET. The Relationship Between Vitamin K and Peripheral Arterial Disease. Atherosclerosis. 2016 Sep;252:15-20.  
  • (11) Beulens JW. High dietary menaquinone intake is associated with reduced coronary calcification. Atherosclerosis. 2009;203:489–493. 
  • (12) Gast GC. A high menaquinone intake reduces the incidence of coronary heart disease. Nutr. Metab. Cardiovasc. Dis. 2009;19:504–510. 
  • (13) Geleijnse JM. Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: The Rotterdam Study. J. Nutr. 2004;134:3100–3105.
  • (14) Hsi RS. Coronary Artery Calcium Score and Association With Recurrent Nephrolithiasis: The Multi-Ethnic Study of Atherosclerosis. J Urol. 2016 Apr;195(4 Pt 1):971-6.
  • (15) Li Y. Vitamin K1 Inhibition of Renal Crystal Formation Through Matrix Gla Protein in the Kidney. Kidney Blood Press Res. 2019;44(6):1392-1403.  
  • (16) Wei FF. The Risk of Nephrolithiasis Is Causally Related to Inactive Matrix Gla Protein, a Marker of Vitamin K Status: A Mendelian Randomization Study in a Flemish Population. Nephrol Dial Transplant. 2018 Mar 1;33(3):514-522.
  • (17) Aengevaeren VL. Fitness and Coronary Artery Calcification. JAMA Intern Med. 2016;176(5):716.
  • (18) Möhlenkamp S. Marathon Study Investigators; Heinz Nixdorf Recall Study Investigators. Running: the risk of coronary events: prevalence and prognostic relevance of coronary atherosclerosis in marathon runners. Eur Heart J. 2008;29(15):1903–1910.
  • (19) Schwartz JG. Does long-term endurance running enhance or inhibit coronary artery plaque formation? A prospective multidetector CTA study or men completing marathons for at least 25 consecutive years. J Am Coll Cardiol. 2010;55(10A)
  • (19) Laddu DR. 25-year physical activity trajectories and development of subclinical coronary artery disease as measured by coronary artery calcium: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Mayo Clin Proc. 2017;92(11):1660–1670.
  • (20) Kermott CA. Cardiorespiratory Fitness and Coronary Artery Calcification in a Primary Prevention Population. Mayo Clin Proc Innov Qual Outcomes. 2019 Jun; 3(2): 122–130.
  • (21) Armstrong  MEG. Frequent Physical Activity May Not Reduce Vascular Disease Risk as Much as Moderate Activity: Large Prospective Study of Women in the United Kingdom. Circulation. 2015 Feb 24;131(8):721-9.
  • (22) Kingsley JD. Arterial stiffness and autonomic modulation after free-weight resistance exercises in resistance trained individuals. Journal of Strength and Conditioning Research 2016 30, 3373–3380. 
  • (23) Kingsley JD. Free-weight Resistance Exercise on Pulse Wave Reflection and Arterial Stiffness Between Sexes in Young, Resistance-Trained Adults. Eur J Sport Sci . 2017 Sep;17(8):1056-1064.
  • (24) García-Mateo P. Effects of Resistance Training on Arterial Stiffness in Healthy People: A Systematic Review. Journal of Sports Science and Medicine (2020) 19, 444 – 451
  • (25) Sato T. MK-7 and Its Effects on Bone Quality and Strength. Nutrients. 2020 Mar 31;12(4):E965.  
  • (26) Juanola-Falgarona M. Dietary Intake of Vitamin K Is Inversely Associated With Mortality Risk
  • J Nutr. 2014 May;144(5):743-50.  
  • (27) Dam V. Association Between Vitamin K and the Metabolic Syndrome: A 10-Year Follow-Up Study in Adults. J Clin Endocrinol Metab. 2015 Jun;100(6):2472-9.
  • (28) Xiangni S. Vitamin K2 Alleviates Insulin Resistance in Skeletal Muscle by Improving Mitochondrial Function via SIRT1 Signaling. Antioxid Redox Signal. 2020 Apr 7.
  • (29) Dash NR. Metagenomic Analysis of the Gut Microbiome Reveals Enrichment of Menaquinones (Vitamin K2) Pathway in Diabetes Mellitus. Diabetes Metab J. 2020 May 11.
  • (30) Cao  AL. [Research Progress of Relationship Between Vitamin K and Type 2 Diabetes]. Zhonghua Yu Fang Yi Xue Za Zhi. 2020 May 6;54(5):555-562.  
  • (31) Li Y. Effect of vitamin K2 on type 2 diabetes mellitus: A review. Diabetes Res Clin Pract. 2018 Feb;136:39-51.
  • (32) Shurgers LJ. Determination of Phylloquinone and Menaquinones in Food. Effect of Food Matrix on Circulating Vitamin K Concentrations. Haemostasis 2000, 30, 298–307. 
  • (33) Schurgers LJ. Vitamin K- containing dietary supplements: Comparison of synthetic vitamin K1 and natto-derived menaquinone-7. Blood 2007, 109, 3279–3283.
  • (34) Schurgers LJ. Differential lipoprotein transport pathways of K-vitamins in healthy subjects. Biochim. Biophys. Acta 2002, 1570, 27–32.
  • (35) Marles RJ. US Pharmacopeial Convention safety evaluation of menaquinone-7, a form of vitamin K. Nutr. Rev. 2017, 75, 553–578. 
  • (36) Theuwissen E. Low-dose menaquinone-7 supplementation improved extra-hepatic vitamin K status, but had no effect on thrombin generation in healthy subjects. Br. J. Nutr. 2012, 108, 1652–1657.  
  • (37) Knapen MH. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women. Osteoporos Int. 2013, 24, 2499–2507. 
  • (38) Knapen MHJ. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial. Thromb. Haemost. 2015, 113, 1135–1144.
  • (39) Kuang X. The Combination Effect of Vitamin K and Vitamin D on Human Bone Quality: A Meta-Analysis of Randomized Controlled Trials. Food Funct. 2020 Apr 30;11(4):3280-3297.  

Reviews

Transparency
Suppliers and
studies available
Conceived in France
& made in Belgium
0% Additives
0% Excipients
100% quality raw materials
Free delivery
to the United Kingdom